Endocrine Abstracts

Background: Pituitary adenomas(PAs) comprise 10%–25% of all intracranial tumors, the majority of them being benign. But 35% of all PAs are considered invasive, having a higher recurrence rate than benign ones.Objectives: We analyzed the expression of different angiogenic growth factors and their receptors in PAs and identified correlations with the hormone profile that could explain their behavior and prognosis.Methods: Our st...

Introduction: Acromegaly is characterized by elevated levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), most often due to a pituitary tumor. Persistent high levels of these hormones lead to a constellation of signs and symptoms and systemic complications associated with increased mortality. A potential association between acromegaly and cancer has been hypothesized regarding colorectal, thyroid, and prostate cancers, but there are few or no descriptions f...